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Findings From International Research Group Show HHV-6 Connection To Energy Production Problems In ME/CFS

Saturday 2 May 2020


From the Solve ME/CFS Initiative (via email):


Solve ME/CFS Initiative

Findings from International Research Group Published in ImmunoHorizons Show HHV-6 Connection to Energy Production Problems in ME/CFS

May 2, 2020
Copyright © 2020 Solve ME/CFS Initiative.

In 2016, Bhupesh Prusty, PhD, a scientist at Julius Maximilians University of Würzburg in Germany, received pilot funding from the Solve M.E. Ramsay Research Grant Program to study the possible cause of dysfunctional mitochondria (energy producers in cells) in ME/CFS.

Dr. Prusty collaborated with an international group of researchers that included Robert Naviaux, MD, PhD, from UC San Diego School of Medicine (who has advanced a theory of “Cell Danger Response” in ME/CFS) and Carmen Scheibenbogen, MD, PhD, from Charité University in Berlin. The research team focused on Human Herpes Virus 6 (HHV-6), which can lie dormant (known as viral latency) in human hosts by integrating with our chromosomes.

The researchers took culture medium from cells in a state of HHV-6 reactivation and applied it to a culture of healthy cells. They observed changes to mitochondrial structures associated with a low metabolic state. The same structural changes were also found when healthy cells were grown in a culture medium containing serum from ME/CFS patients. Removal of the ME/CFS patients’ serum from the cells resulted in the mitochondria exhibiting signs of proper functioning.


Full article…



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