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Fibromyalgia Linked To Worse Cognitive Function, 'Fibrofog'

Wednesday 6 November 2019


From Healio Rheumatology:



Fibromyalgia linked to worse cognitive function, 'fibrofog'

Kratz AL, et al. Arthritis Care Res. 2019;doi:10.1002/acr.24089.
November 5, 2019
©2019 Healio All Rights Reserved.

Patients with fibromyalgia demonstrate worse objective and subjective cognitive function — sometimes called “fibrofog” — compared with individuals without the disease, according to data published in Arthritis Care & Research.

“This is the first study to examine both subjective, or perceived, as well as objective, or performance, aspects of cognitive dysfunction in the daily lives of people with fibromyalgia,” Anna L. Kratz, PhD, of the University of Michigan, in Ann Arbor, told Healio Rheumatology. “Prior to this study, cognitive functioning in fibromyalgia has been studied exclusively in the laboratory, using standard neuropsychological testing protocols, administered by a trained examiner in a quiet, controlled testing environment.”

“The protocols are limited by the artificial testing environment, which is very unlike the natural environment that people live their lives and in which ‘fibrofog’ is experienced,” she added. “The other limitation of lab-based testing is that it is unable to capture natural fluctuations in cognitive functioning. This way of measuring cognitive functioning is in stark contrast to how people experience fibrofog — reporting good times, when their thinking is relatively fast and clear, and bad times, when their thinking is foggy and slow.”

To analyze cognitive function, as well as the association between subjective and objective aspects of cognition, among patients with and without fibromyalgia, Kratz and colleagues recruited 100 adults from the University of Michigan. Among the participants, 50 had a diagnosis of fibromyalgia while the remaining 50 were controls who were matched based on age, sex and education.


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