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ME/CFS SOUTH AUSTRALIA INC

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Home > In the News > 2018 > July > Seminar Report: Cardiopulmonary Alterations In ME/CFS

Seminar Report: Cardiopulmonary Alterations In ME/CFS

Wednesday 11 July 2018

From Society member Bronwyn Caldwell:

Cardiopulmonary Alterations in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

By Bronwyn Caldwell
Wednesday 11 July 2018

Intro:

Following our AGM on Saturday 18 November 2017, Dr. Max Nelson spoke to us about his very recently completed PhD. He had only finished that same week & was having a get together to celebrate directly after our seminar, so we were very grateful he was able to make time to pop in and speak to us.

Key Takes Outs:

Max’s background is in exercise physiology. Specifically looking at fatigue and the negative effects it has on the performance of athletes. He and his team had previously looked at the VO2 Max test to find markers of incomplete recovery from exercise in athletes.
Ultimately the best indicator of an athlete not being fully recovered from previous exertion was found to be heart rate increase (HRI).
For his PhD, Max chose to look at whether the VO2 Max test, when performed 2 days in a row, could produce a reliable indicator of ME/CFS induced post exertional malaise (PEM). This form of the VO2Max test is also known as the two-day bike test.
If found, a PEM marker could be used to diagnose ME/CFS and also improve treatment and management of the disease.
While most of the measures showed no significant differences between the trial and control groups, and there was no evidence of deconditioning in the ME/CFS patients, one measure was found that looks promising: work rate at ventilatory threshold.
This needs to be validated by other research teams replicating the work and the potential for the test to exacerbate patients’ symptoms evaluated.