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Brain Imaging And Behavior Publication From Dr. Jarred Younger's SMCI Ramsay Pilot Study Supports Involvement Of Neuroinflammation In ME/CFSWednesday 16 January 2019
From the Solve ME/CFS Initiative (via email):
Brain Imaging and Behavior publication from Dr. Jarred Younger’s SMCI Ramsay pilot study supports involvement of neuroinflammation in ME/CFS The researchers found markers of widespread neuroinflammation and metabolite abnormalities in the first whole-brain Magnetic Resonance Spectroscopy study of individuals with ME/CFS
“Metabolite and temperature abnormalities were distributed across large portions of the brain, and are consistent with global neuroinflammation” Researchers from the Neuroinflammation, Pain and Fatigue Laboratory, led by Jarred Younger (PhD) at the University of Alabama at Birmingham, and University of Miami Miller School of Medicine radiology experts published a new ME/CFS study in Brain Imaging and Behavior. With seed funding from SMCI’s Ramsay Award Program, the researchers brought novel use of a neuroimaging tool, magnetic resonance spectroscopy (MRS), to examine inflammatory processes at work in the brains of people with ME/CFS. Dr. Younger’s pilot study provides compelling evidence that low-level neuroinflammation - present across a range of brain areas - is a factor in ME/CFS. The results corroborate previous observations of brain abnormalities, including elevated lactate, and extend findings from MRS studies that were limited to specific regions. Fulfilling a key goal of the Ramsay Award program, the data was recently used in a proposal to the National Institutes of Health to run an expanded study.
Read the full study here, and get a breakdown below. What you need to know:
→ Want more information about the work of Dr. Younger? Watch an SMCI Science & Discovery webinar featuring a discussion with Dr. Younger below and check out coverage from Cort Johnson’s Health Rising blog here.
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