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Is some "treatment-resistant depression" actually Chronic Fatigue Syndrome?

Wednesday 29 January 2014


From's Adrienne Dellwo:



Is Some "Treatment-Resistant Depression" Actually Chronic Fatigue Syndrome?

By Adrienne Dellwo
January 24, 2014

If you have chronic fatigue syndrome (ME/CFS), you're probably aware that some doctors will blow off your diagnosis and consider you "just" depressed. New research turns that thinking on its head, suggesting that some cases labeled "treatment-resistant depression" are, in fact, undiagnosed ME/CFS. The recommended treatment? An anti-viral medication.

Fifteen adolescents and preteens were referred to the doctor who authored the study. All were diagnosed with treatment-resistant depression or mood disorders. However, the doctor discovered they all met the Fukuda diagnostic criteria for ME/CFS even though only 4 of them had been diagnosed with it.

In further testing, the doctor found that most of the kids didn't even meet the criteria for depression.

All of them were treated with the anti-viral drug valacyclovir, and all but one had a positive response. The author reports that fatigue dropped significantly and some had symptoms resolve completely.

Natural killer cell counts increased, and human herpesvirus 6 antibody titers decreased in all those who were both tested (not all were) and responded positively to the drug.

The author says the data support the hypothesis that some diagnoses of treatment-resistent depression may actually be undiagnosed ME/CFS or another chronic viral infection, and symptoms labeled psychiatric may have a pathological cause.



The above, with comments, originally appeared here.



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