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Metal allergy can trigger Fibromyalgia
Friday 10 January 2014
Metal Allergy Can Trigger Fibromyalgia
Metal-induced inflammation triggers fibromyalgia in metal-allergic patients.
By V. Stejskal, K. Ockert and G. Bjørklund.
BACKGROUND: Fibromyalgia (FM) is a disease of unknown etiology. Inflammation could be one of the mechanisms behind this disease.
OBJECTIVES: We studied the frequency and clinical relevance of metal allergy in FM patients.
METHODS: Fifteen female FM patients were included in the study. Metal allergy was measured by a lymphocyte transformation test, MELISA®. Ten healthy age-matched women were used as controls for in vitro studies. Reduction of metal exposure in the FM patients was achieved by replacement of dental metal restorations and by the avoidance of known sources of metal exposure. Objective health assessment was performed 5 years after treatment. Subjective health assessment was established by a questionnaire, completed 2, 5 and in some cases 10 years after the start of the study. Follow-up MELISA was also performed.
CONCLUSION: Metal allergy is frequent in FM patients. The reduction of metal exposure resulted in improved health in the majority of metal-sensitized patients. This suggests that metal-induced inflammation might be an important risk factor in a subset of patients with FM.
Source: Neuro Endocrinology Letters, November 2, 2013. By V. Stejskal, K. Ockert and G. Bjørklund.
The above originally appeared here.
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