Society Logo
ME/CFS Australia Ltd
Please click here to donate ME/CFS Australia (SA) Inc
 
 
Facebook
 
ME/CFS AUSTRALIA (SA) INC

Registered Charity 698

Email:
sacfs@sacfs.asn.au

Mailing address:
PO Box 28,
Hindmarsh,
South Australia 5007

Office:
Suite 506,
North Terrace House,
19 North Terrace,
Hackney, SA, 5069


Phone:
1300 128 339

Office Hours:
Wednesdays, 11am-3pm

ME/CFS Australia (SA) Inc supports the needs of sufferers of Myalgic Encephalomyelitis, Chronic Fatigue Syndrome and related illnesses. We do this by providing services and information to members.

Disclaimer

ME/CFS Australia (SA) Inc aims to keep members informed of various research projects, diets, medications, therapies, news items, etc. All communication, both verbal and written, is merely to disseminate information and not to make recommendations or directives.

Unless otherwise stated, the views expressed on this Web site are not necessarily the official views of the Society or its Committee and are not simply an endorsement of products or services.

Become a Member
PDF Application Form (PDF, 277KB)
Why become a member?

Quality of life for Fibromyalgia patients worsens after taking antidepressants for a year

Wednesday 11 September 2013

 

From ProHealth:

 

TabletsQuality of Life for Fibromyalgia Patients Worsens after Taking Antidepressants for a Year

ProHealth.com • September 9, 2013

Editor's comment: This was a very small observational study. Just 18 patients completed the study and only seven of those were in the group taking antidepressants (five took an SNRI and two took an SSRI). However, the finding that these patients' quality of life worsened when taking antidepressants for a year is concerning – especially since two of the three drugs approved by the FDA for treating fibromyalgia are SNRI antidepressants. Additional larger studies are warranted.

Note: You may read the full text of this article free HERE.


The Use of Antidepressants in the Long-Term Treatment Should not Improve the Impact of Fibromyalgia on Quality of Life

Abstract:

Background: Antidepressant (AD) drugs are effective in the short term treatment of fibromyalgia (FM). It may be useful to study the long-term impact of AD on patients with FM.

Methods: One-year follow-up study on 23 females with FM divided into groups on AD (ADg-N=7), and not taking AD (NADg-N=11). Evaluation at t1 and at the end (t2) with the Fibromyalgia Impact Questionnaire (FIQ); at t2 with: SCID-IV; Mood Disorder Questionnaire (MDQ); Short Form-12; Hamilton Depression Rating Scale (HAM-D); Functioning Assessment Short Test (FAST)

Results:

  • After a year the AD group showed a worst impact of the disease by FIQ (p=0.017),

  • worsened quality of life by SF-12 (p<0.01),

  • and disability linked to bipolar symptoms by FAST (p=0.05).

  • About 40% of the sample was screened positive at MDQ without difference in the two groups.

  • The patients who recovered from a depressive episode did not differ between ADg and NADg (20% vs 33.3%), and were fewer than expected from the literature (40-60%).

  • The HAM-D score at the end of the trial was worse in the ADg (p<0.03).

Limitations: Observational research on few patients, not specifically designed to test the hypothesis. The results have a heuristic value only.

Discussion: The results should be read in the light of the high prevalence of patients screened positive for Bipolar Disorders and of the well-known poor response of the mood symptoms to antidepressants in Bipolar Depression. The deterioration in the long-term management of FM patients following AD treatments suggests the need for new and robust studies.

Source: Clinical Practice and Epidemiology in Mental Health, July 12, 2013. By M.G. Carta,, V. Ruggiero, F. Sancassiani, F. Cutrano, A.R. Manca, M. Peri, A. Fais, and E. Cacace. Dipartimento di Sanità Pubblica e Medicina Clinica e Sperimentale, Università di Cagliari e Center of Liaison Psychiatry and Psychosomatics, University Hospital of Cagliari, Italy.

 

The above originally appeared here.

 


Arrow right

More Fibromyalgia News

 


 

blog comments powered by Disqus
Previous Previous Page