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CFS: Possible diagnostic markers

Saturday 12 September 2009

Test tubesAdrienne Dellwo reports on some encouraging new research:

RESEARCH BRIEF: Two different research teams have recently identified blood biomarkers for
chronic fatigue syndrome (CFS or ME/CFS), something that could eventually be used to make diagnoses.

A research team at the University of Utah Health Sciences Center has identified genes that become more active after moderate exercise. This work was done on mice, but researchers say it provides an hypothesis for comparing the blood of people with ME/CFS to that of healthy people to examine the genetic activity. This is one of several teams working on diagnostic markers that result from post-exertional malaise, a key symptom of ME/CFS.

Read more about it: Blood Biomarkers for CFS: A Light at the End of the Tunnel

Separately, researchers at the University of Hawaii say they've also found a possible diagnostic marker for ME/CFS as well as evidence that ME/CFS may be an autoimmune condition. They found a type of anticardiolipin antibodies (ACAs) in the sera (a component of blood) in 95% of test subjects with ME/CFS. They say this suggests the possibility of changes to liver mitochondria.

See the full paper: Anticardiolipin Antibodies in the Sera of Patients with Diagnosed Chronic Fatigue Syndrome [PDF]

The article originally appeared here.



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