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ME/CFS Australia Ltd
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Registered Charity 3104


ME/CFS South Australia Inc supports the needs of sufferers of Myalgic Encephalomyelitis, Chronic Fatigue Syndrome and related illnesses. We do this by providing services and information to members.


ME/CFS South Australia Inc aims to keep members informed of various research projects, diets, medications, therapies, news items, etc. All communication, both verbal and written, is merely to disseminate information and not to make recommendations or directives.

Unless otherwise stated, the views expressed on this Web site are not necessarily the official views of the Society or its Committee and are not simply an endorsement of products or services.

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Medical articles

Basic information
ME/CFS: a basic overview (PDF, 57KB)
Overlap between CFS & other symptom-based syndromes (PDF, 19KB)
Multiple Chemical Sensitivity (PDF, 32KB)
MCS: Basic Overview (PDF, 18KB)
Fibromyalgia Syndrome (PDF, 34KB)

Information for ME/CFS physicians
Autonomic function in CFS (PDF, 32KB)
Cardiovascular Function & Exercise in CFS (PDF, 33KB)
ME/CFS Guidelines: Management Guidelines for General Practitioners (PDF, 460KB)
ME/CFS: Basic Facts for General Practitioners (PDF, 18KB)
Cognitive Function in CFS (PDF, 32KB)
Research Definition of CFS, known as the CDC or Fukuda (1994) [external link]

Miscellaneous articles
CFS-like states (Jan 6, 2005)
Grade Exercise Therapy for ME… or you? (Mar 2001)
Adelaide research into CFS, fibromyalgia, & brain fog (Sep 22, 2004)

Adelaide research 2: lactate threshold during exercise

See also:

Adelaide University research 1: lactic acid

Adelaide University research 3: total body potassium

The following information was supplied as part of a handout at the November 7 talk given by Professor Garry Scroop at the AGM of the ME/Chronic Fatigue Syndrome Society of Victoria Inc:

Normal aerobic capacity and lactate threshold during incremental exercise in patients with chronic fatigue syndrome

By G C Scroop, R B Burnet, B Yeap, J D Buckley, S S Lim, and T Ho

Exercise Physiology Research Unit, Department of Physiology, Unversity of Adelaide, SA 5005

November 7, 2004

The metabolic responses during incremental exercise to exhaustion in 5 patients with Chronic Fatigue Syndrome (CFS) were compared with 5 healthy sedentary controls matched for gender (3 female, 2 male), age (CFS 34.80 +/- 4.73; controls, 35.20 +/- 4.59, yr), height (CFS, 170.40 +/- 4.39; controls 171.70 +/- 5.00, cm) and mass (CFS, 72.12 +/- 9.58; controls, 76.58 +/- 9.80, kg).

Control subjects exercised for longer (CFS, 18.80 +/- 0.58; controls, 23.66 +/- 1.01,min p<0.006), reached a higher peak workload (CFS, 125.00 +/- 7.91; controls 165.00 12.75, watts, p<0.04), and consequently did more work (CFS, 67.20 +/- 8.78; controls, 114.45 +/- 16.58, kJ, p<0.05).

Peak VO2 (VO2peak) at exhaustion was not significantly different between these 2 subject groups (CFS, 28.01 +/- 1.93; controls, 35.23 +/- 3.54;, NS) or from their predicted VO2max determined during an earlier submaximal cycling test (CFS, 29.87 +/- 1.36; controls, 33.34 +/- 3.76;; NS).

VO2peak achieved at peak heart rates (Hrpeak) which were not significantly different from each other (CFS, 177+/- 5; controls, 180 +/- 6; beats.min-1) or from their age-predicted maximum heart rates (Hrmax; CFS, 185 +/- 5; controls, 185 +/- 5; beats.min-1; NS).

The lactate threshold (LT, determined from a log-log plot of absolute VO2 versus blood lactate concentration) occurred at VO2 levels which were not significantly different between the 2 groups whether expressed in relative (CFS, 14.53 +/- 1.26; controls 14.16 +/- 2.05 or percentage (CFS, 52.2 +/- 3.4; controls, +41.9 +/- 7.8; % VO2peak) terms.

Despite doing less work the blood lactate concentration (CFS, 4.54 +/- 0.84; controls, 6.38 +/- 0.36; mmol.l-1) and VO2 at exhaustion in patients with CFS were not different from controls.

It is concluded that while the work capacity of patients with CFS is significantly less than sedentary controls, aerobic capacity and the LT are not, suggesting that factors other than so-called “deconditioning” are responsible for the earlier fatigue during exercise.

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